SPL RESOURCES: Download All Drug Labels

Choose from daily, weekly or monthly periodic updates or full releases of all drug labels. Downloads are available as zip files.

Periodic Updates

MONTHLY WEEKLY DAILY

• dm_spl_monthly_update_mar2025.zip [ HTTPS / FTP ]
  • Number of labels: 4,123
  • File size: 1.54GB
  • MD5 checksum: 2c373bb6cd92c4183b0d9171be77a45f
• dm_spl_monthly_update_feb2025.zip [ HTTPS / FTP ]
  • Number of labels: 4,031
  • File size: 1.56GB
  • MD5 checksum: 4cf1ce490c973cde084dab422ee5fb23
• dm_spl_monthly_update_jan2025.zip [ HTTPS / FTP ]
  • Number of labels: 7,670
  • File size: 2.58GB
  • MD5 checksum: 3974bb282aaa814ace053fc498ae8135
• dm_spl_monthly_update_dec2024.zip [ HTTPS / FTP ]
  • Number of labels: 10,396
  • File size: 3.58GB
  • MD5 checksum: ab23a7acda78af9de1a5367c461a55de
• dm_spl_monthly_update_nov2024.zip [ HTTPS / FTP ]
  • Number of labels: 8,038
  • File size: 2.67GB
  • MD5 checksum: a198163c8fae036fb8855d4b9f2a7fbf
• dm_spl_monthly_update_oct2024.zip [ HTTPS / FTP ]
  • Number of labels: 9,801
  • File size: 256.25MB
  • MD5 checksum: b8211ed1d91638e5315e5af4e8785c32
• dm_spl_monthly_update_sep2024.zip [ HTTPS / FTP ]
  • Number of labels: 4,493
  • File size: 1.39GB
  • MD5 checksum: 055959e7063e05c73e2aa56f6cf0aa8a
• dm_spl_weekly_update_041425_041825.zip [ HTTPS / FTP ]
  • Number of labels: 835
  • File size: 352.63MB
  • MD5 checksum: 14df27c3bbe6047d8f6d678a690aac32
• dm_spl_weekly_update_040725_041125.zip [ HTTPS / FTP ]
  • Number of labels: 1,266
  • File size: 456.26MB
  • MD5 checksum: 3703a3771f250d3fedf630422921c04d
• dm_spl_weekly_update_033125_040425.zip [ HTTPS / FTP ]
  • Number of labels: 901
  • File size: 293.53MB
  • MD5 checksum: 328897cdb98cca41cc40b0ef2a2fea58
• dm_spl_daily_update_04222025.zip [ HTTPS / FTP ]
  • Number of labels: 18
  • File size: 6.17MB
  • MD5 checksum: 5021b798adfb75641050568029b914f8
• dm_spl_daily_update_04212025.zip [ HTTPS / FTP ]
  • Number of labels: 151
  • File size: 61.97MB
  • MD5 checksum: ed9a3e24faa55570dd4df93040d97f6e

Full Releases

Warning: The full human prescription and OTC archive files, dm_spl_release_human_rx.zip and dm_spl_release_human_otc.zip, are no longer available due to size considerations. Instead, these archives have been split into multiple parts. The remainder archive files consist of bulk ingredient labels, vaccine labels, and some labels for medical devices.

HUMAN PRESCRIPTION LABELS HUMAN OTC LABELS HOMEOPATHIC LABELS ANIMAL LABELS REMAINDER LABELS

• dm_spl_release_human_rx_part1.zip [ HTTPS / FTP ]
  • Number of files: 15,101
  • File size: 3.00GB
  • MD5 checksum: 4fbed3cd4cff5a3eb50a20c130540986
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_rx_part2.zip [ HTTPS / FTP ]
  • Number of files: 10,535
  • File size: 3.00GB
  • MD5 checksum: b07668b44b6ee6ec6ac6df0f09d2ae75
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_rx_part3.zip [ HTTPS / FTP ]
  • Number of files: 9,129
  • File size: 3.00GB
  • MD5 checksum: a0590e8dfd05d040e03358bbd5abdf16
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_rx_part4.zip [ HTTPS / FTP ]
  • Number of files: 9,320
  • File size: 3.00GB
  • MD5 checksum: 1de7da3cf981459974f170b172681b3a
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_rx_part5.zip [ HTTPS / FTP ]
  • Number of files: 6,509
  • File size: 2.32GB
  • MD5 checksum: 0405340beeb3280c659a6a195919e591
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part1.zip [ HTTPS / FTP ]
  • Number of files: 12,284
  • File size: 3.00GB
  • MD5 checksum: f12214bd606ee5cbd722dd1d9310485f
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part2.zip [ HTTPS / FTP ]
  • Number of files: 8,936
  • File size: 3.00GB
  • MD5 checksum: 29ec588e592be290116151c0fc671cb9
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part3.zip [ HTTPS / FTP ]
  • Number of files: 6,322
  • File size: 3.00GB
  • MD5 checksum: 32a0b5bcda3c54ed9af54c8cc4872f71
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part4.zip [ HTTPS / FTP ]
  • Number of files: 5,979
  • File size: 3.00GB
  • MD5 checksum: 3eaa4a143a58725f61809a65be217837
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part5.zip [ HTTPS / FTP ]
  • Number of files: 7,374
  • File size: 3.00GB
  • MD5 checksum: 7dbbc28566f23bcb57f726478f3622e1
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part6.zip [ HTTPS / FTP ]
  • Number of files: 7,319
  • File size: 3.00GB
  • MD5 checksum: 5ffbaeeefc9cefa0c1dd3b7ae8fcc775
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part7.zip [ HTTPS / FTP ]
  • Number of files: 8,271
  • File size: 3.00GB
  • MD5 checksum: 81d0d7f199a8899db2005dfcd26fd713
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part8.zip [ HTTPS / FTP ]
  • Number of files: 10,189
  • File size: 3.00GB
  • MD5 checksum: 2e88cd43331de38b752f94b18b7bf5c5
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part9.zip [ HTTPS / FTP ]
  • Number of files: 8,489
  • File size: 3.00GB
  • MD5 checksum: ce39f70a5319428ea189bd2e21fbd8a2
  • Last Modified: Apr 22, 2025
• dm_spl_release_human_otc_part10.zip [ HTTPS / FTP ]
  • Number of files: 6,828
  • File size: 2.59GB
  • MD5 checksum: ad38da635977cbe7546f5822628fdd88
  • Last Modified: Apr 22, 2025
• dm_spl_release_homeopathic.zip [ HTTPS / FTP ]
  • Number of files: 15,821
  • File size: 5.28GB
  • MD5 checksum: bcae9b40f89761725ac6c9305c04d23a
  • Last Modified: Apr 22, 2025
• dm_spl_release_animal.zip [ HTTPS / FTP ]
  • Number of files: 3,273
  • File size: 1.01GB
  • MD5 checksum: 9146a761ce73d385824f411702ed7efc
  • Last Modified: Apr 22, 2025
• dm_spl_release_remainder.zip [ HTTPS / FTP ]
  • Number of files: 2,271
  • File size: 541.99MB
  • MD5 checksum: 1505893d89ee61454fdfffee8d20a2c6
  • Last Modified: Apr 22, 2025